Beautiful CEO becomes first gene therapy experimenter: telomere lengthening 0.62kb, cells reverse age by 20 years!

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01 Beautiful CEOs are willing to be mice for research

Human beings are not helpless in the face of telomere changes.

In 2012, Professor Maria Blasco, a leading Spanish academic, used the telomerase reverse transcriptase gene in an experiment that successfully extended the life span of mice by 24%, pioneering gene therapy to fight aging. The FDA has issued a rule that "in order to start a clinical study, some preclinical trials must be completed" because the safety of the technology has yet to be proven.

The FDA's "warning" didn't go over well with rich biohackers, and in 2015, Elizabeth Parrish, the 44-year-old CEO of the US biotech company BioViva, flew to Colombia to undergo two controversial experimental gene therapies. experimental gene therapies. A year later, the company issued a statement saying that the physiological age of Parrish's immune cells had been reversed by 20 years.

In the experiments, Parrish injected his own cells with the TERT gene, which promotes the production of telomerase by cells to extend telomere length, resulting in lifespan extension. After a six-month experimental period, Parrish's telomere length increased from 6.71 kb to 7.33 kb, which translates into a physiological age of the cell, about 20 years younger, according to the SpectraCell Clinical Testing Facility in Houston.

In fact, there have been many questions about the safety of gene therapy in recent years, and the high cost of the treatment has led to suspicions that Parrish is "hype" for its own product.

In response to the questions, Parrish said in an interview: "Just because something isn't fully proven doesn't mean you can't try it. If humans can switch from treating illness to preventing it early, they are saving money by extending their lives.

Publicly available information shows that the cost of gene therapy typically ranges from hundreds of thousands to millions of dollars. In the future, this technology may become another tool for humans to fight aging, only at this stage, the average person seems unable to afford its trial-and-error costs.

Now that telomeres can measure human life expectancy, how to test them scientifically has become another hot topic of debate in academia.

02 Know your body so you can control it

In his autobiography, Harvard genetics professor David Sinclair states that you need to know your body so you can control it better. People need to have their body data tested regularly to fight aging, otherwise it's like driving a car without a dashboard.

Compared to the crazy attempts of Western biohackers, domestic tycoons are much more introspective. The founder of Leysin Tongling Jewelry, Shen Dongjun, had microblogged telomere test data, saying bluntly, "Whether the body is good or not, not only depends on the physical examination report, the physiological age can be measured by telomere testing."

Throughout China, it seems that the only one that can achieve professional telomere testing and provide a valid database is TimePatch. Upon investigation, TimePatch has formed a biomedical team with backgrounds from prestigious universities at home and abroad, and is a pioneer in aging service management in China.

It is easy to see from the report published by Shen Dongjun that it is the Time Ruler Telo²™ telomere assay that is used. It uses a TRF measurement method that has been hailed as the "gold standard of telomere detection" in academia. It is characterized by molecular-level precision and ultra-low error in detecting the most realistic telomere length in the human body.

It is true that the rich have always been the first users of cutting-edge technology. Even the chairman of a publicly traded company with billions in market capitalization in hand still finds time to focus on his body data. According to TimePatch staff, Shen Dongjun said bluntly after listening to the aging test interpretation report: the significance of this product is not to extend life, but to warn me to fear life.

Industry insiders point out that this is the first product in China to bring the vague concept of telomere measurement to the ground, and TimePatch claims to be a pioneer in the domestic anti-aging field. A search of the Time Ruler series pricing seems to have broken the barrier between the average person and the rich and famous, yet not everyone pays a thousand dollars for life.

"Measuring telomere length would cost me half a month's salary, and a 5-figure testing service is even more unthinkable," clearly there are still people in need who are being kept out of the door. The wealthy have always spent a lot of energy and money protecting themselves from potential threats, separating themselves from the general population and doing everything they can to extend their lives.

Longevity has also evolved in this era into a privilege for the rich.

03 One step closer to longevity

The American Journal of Medicine noted in a study that wealthy people with more than $50 million are willing to share almost half of their wealth to achieve a balance with longevity.

The rich are generally willing to pay for a longer life span, and the emergence of an income inequality "divide" means that life expectancy will be unequal as well. Living to 100 is a sincere expectation, which requires more health care, exercise, food, and other services that can extend life.

There are, as in the case of the Time School, pricey aging management services that many ordinary people like you and me are inevitably torn about their attitudes. It's just a matter of feeling your way through, selectively making efforts like sticking to exercise and eating healthy.

To be sure, every little bit of change for anti-aging may mean a little bit closer to longevity.