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The 58-year-old Mr. Wang, ten years ago, the physical examination of high blood pressure, then the blood pressure value of up to 170/98mmHg, the doctor gave him a long-acting antihypertensive drugs, and urged him to take once a day, the blood pressure can be stable decline.
This decade, Mr. Wang has been taking his antihypertensive medication on time, but last month he experienced nausea and vomiting, body edema, and loss of appetite. After going to the hospital, but found that urine protein positive, blood uric acid, blood creatinine and other indicators abnormally high, the glomerular filtration rate of only 35ml/min, but ultimately diagnosed as chronic renal failure.
Mr. Wang was puzzled by the fact that he had been taking blood pressure medication for a long time, so why did he get kidney failure?
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Doctors realized that after a year of taking the medication, he went to the pharmacy to buy the medication and found that the price of another short-acting medication was much cheaper, so he thought that he would take the medication, and the result would be similar.
These drugs have been used three times a day, but moncler jackets sale only once, and the blood pressure is definitely not coming down.

One, the wrong medication kills 200,000 people a year?

A statistic from the former State Food and Drug Administration shows that 2.5 million people in China damage their health every year due to wrong medication, of which 200,000 people die as a result; another national adverse drug reaction data released by the State Drug Administration shows that in 2020, a total of 1,676,000 report forms were received for national adverse drug reactions.
The Chinese Pharmaceutical Association has conducted statistics on the use of medication by the elderly, and found that 56.5% of the elderly do not use medication in accordance with the treatment program, 46.1% combine multiple medications, 45% do not regularly check the shelf life of the drugs, 36.6% do not understand the adverse drug reactions, 13.6% do not read the instructions before using the medication, and 13.5% do not understand the therapeutic effect of the medication.
In this regard, Harbin Medical University Affiliated Hospital No. 1 Pharmacy Department, director of the pharmacist Song Yongxi pointed out that many older people with medication there are three misunderstandings:
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One is the experience of random use of medication: I believe that this point is a lot of people in the body of the problem. Such as after a cold will take antibacterial drugs, or feel that the drug is not strong, will increase the dosage, but the occurrence of colds is due to viral infections caused by the taking of antibacterial drugs in this case is naturally ineffective.
The second is to take a variety of drugs at the same time and the risk of misuse of drugs: the elderly have more or less chronic diseases, often need to take a variety of drugs, but some of the elderly did not follow the doctor's instructions to use the drug, a variety of drugs at once, which may result in the failure of the drug or generation of adverse reactions to the health of the threat.
The other long-term not to take the drug classification and organization, and even some elderly people directly with a paper bag medicine, only according to the impression of the drug, so it is easy to misuse.
Third, the health care products and drugs taken together: health care market is very diverse, many older people in order to maintain health will buy a variety of health care products, and will even be and Western medicine, traditional Chinese medicine, together with the joint use. But the joint use of different drugs, it is likely to produce adverse reactions, threatening health.
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Two, these commonly used drugs mixed, the danger of uninvited

Some of the elderly suffering from chronic diseases, the need to take medication for a long time, but some of the drugs mixed, not only reduces the effectiveness of the drugs, but also may jeopardize the health of the following common medications, in particular, don't mix and eat.
1, cold and flu medicine and cold medicine
Cold and flu medicines are represented by Vicodin tablets, acetaminophen extended-release tablets, etc., most of these drugs within the acetaminophen component, blindly combined with an adverse reaction may induce liver damage, and may even lead to liver failure and death.
2, non-steroidal anti-inflammatory drugs mixed
Non-steroidal anti-inflammatory drugs are ibuprofen, naproxen, indomethacin, etc., the mechanism of action of these drugs are very similar to the joint use of medication will lead to side effects, the lesser of which is caused by nausea, vomiting, and the greater of which is to induce gastrointestinal bleeding. And non-steroidal drugs will react with antihypertensive drugs, so that the antihypertensive effect of the drug is discounted.
3, cephalosporin drugs and alcohol
Some alcohol-containing drugs, such as patchouli can not be taken with cephalosporin. Cephalosporin drugs will inhibit the production of acetaldehyde dehydrogenase, easy to let the drinker's body of acetaldehyde accumulation, induced disulfiram-like reaction. Specifically can be manifested as facial flushing, dizziness, vomiting, dyspnea, etc., serious and may also threaten life.
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4, iodine and red potion
These two drugs are disinfectant, many people feel are disinfectant, 1 +1>2. In fact, the two can not be used together. Iodophor has a large amount of iodine, red potion has a mercury component, the joint use will form mercury iodide, deposited on the surface of the skin, to the skin to bring toxic side effects.
5, statin lipid-lowering drugs and roxithromycin
Statin drugs into the body need to be metabolized by CYP3A4 enzyme, and roxithromycin will inhibit CYP3A4 enzyme. The combination of the two drugs will lead to an increase in blood concentration, which can easily cause rhabdomyolysis to occur.
6, antihypertensive drugs and cold medicine
The joint use of antihypertensive drugs and cold medicine will lead to a reduction in the effect of antihypertensive, for the need of joint use of drugs for the people, the best use of medication and the doctor to explain the specifics of the doctor's orders.
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Three, these six drugs once eaten, can not just stop!

For some people suffering from chronic diseases, daily medication must not be stopped at will, especially these drugs, before stopping the drug must consult the doctor's opinion.
Antihypertensive drugs are needed by hypertensive patients for a long time, and stopping the drugs blindly will lead to a sudden rise and fall in blood pressure, which can easily lead to cardiovascular diseases.
Including nitroglycerin, cardiac pain and other drugs, blindly stopping the drug may lead to coronary artery spasm, induced angina pectoris, and even infarction occurs.
Glucose-lowering drugs include metformin, acarbose, and reglanatide, and some patients need to inject insulin to lower blood sugar, no matter what kind of drugs can not be arbitrarily stopped. The drug is easy to cause blood sugar to rise within a short period of time, which can easily cause ketoacidosis, threatening the patient's life safety.
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Glucocorticosteroids are anti-inflammatory, anti-allergic, anti-shock, etc., and stopping the drug blindly may result in the recurrence and deterioration of the original disease, adrenal cortical atrophy, and insufficiency.
Hepatitis B is a chronic disease, blindly stopping the drug will lead to the suppression of the hepatitis B virus rebound, easy to induce serious liver damage, and may even lead to patients with liver failure, death.
Tuberculosis drugs need to be taken for 6 to 8 months for complete treatment, and still need to be continued after the symptoms disappear. Stopping the drugs too soon will easily lead to recurrence of the disease, and may also cause advanced tuberculosis and total disseminated tuberculosis, which will bring greater difficulty to complete treatment.
The phrase "three poisons in one medicine" is based on science, and no matter what drugs you use in your life, you should follow the doctor's instructions to avoid improper use of medication to bring unnecessary effects on the body.
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